产品货号：
Z38490
中文名称：
TPMT抗体
英文名称：
Anti-TPMT Antibody (Clone#OTI5B4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TPMT Antibody (Clone#OTI5B4) |
| 指标别名 | Thiopurine methyltransferase;thiopurine S methyltransferase;TPMT |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | TPMT |
| 克隆号 | OTI5B4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell. |
| 实际分子量 | 28.2KD |
| 成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene.This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct.Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents.Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals,causing thiopurine S-methyltransferase deficiency.Related pseudogenes have been identified on chromosomes 3,18 and X. |
| Uniprot ID | P51580 |
| 基因名全称 | thiopurine S-methyltransferase |
| 蛋白名全称 | Thiopurine S-methyltransferase |
| 推荐稀释比 | Western blot (WB) 1:1000 Immunohistochemistry in paraffin section (IHC) 1:50 |
相关搜索：TPMT抗体，TPMT单抗，Anti-TPMT Antibody (Clone#OTI5B4)